HSA updates on products found overseas that contain potent ingredients (March 2020)

The Well being Sciences Authority (HSA) want to replace the general public on merchandise which were discovered and reported by abroad regulators in March 2020 to include potent elements which aren’t allowed in these merchandise and will trigger unwanted side effects. This info is offered to extend consciousness on issues of safety of such merchandise discovered abroad, which can influence the native inhabitants. Please seek advice from Annex A and Annex B for the record of merchandise and the potential unwanted side effects of the potent elements. Please seek advice from the pdf doc for photos of the merchandise.

2 Members of the general public are suggested to:

  • Seek the advice of a physician if in case you have consumed any of the merchandise and are feeling unwell.
  • Keep away from shopping for any of the merchandise when overseas.
  • Train warning when buying well being merchandise on-line or from sources (both native or abroad) which you might not be aware of, even when well-meaning associates or family members have advisable them. You can’t be sure the place and the way these merchandise had been made. They might be unlawful, counterfeit or substandard, and will include potent elements which may hurt your well being. If shopping for well being merchandise on-line, we encourage you to purchase them from web sites with a longtime retail presence in Singapore.
  • Be cautious of merchandise that promise fast and miraculous outcomes or carry exaggerated claims like “100% secure”, “no unwanted side effects” or “scientifically confirmed”. Customers must also be cautious of merchandise that produce sudden fast restoration of medical circumstances.
  • Seek the advice of your physician or pharmacist in the event you need assistance for the administration of your acute and persistent medical signs and circumstances (e.g. diabetes, hypertension, eczema).
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3 Moreover, members of the general public are inspired to go to https://www.hsa.gov.sg/consumer-safety/ to be taught extra in regards to the risks of shopping for well being merchandise from doubtful sources.

4 Members of the general public who come throughout the sale and provide of those merchandise in Singapore could contact HSA’s Enforcement Department at Tel: 6866 3485 throughout workplace hours (Monday to Friday) or e mail: [email protected]

Record of Merchandise

Notice: There could also be totally different variations or variants of the merchandise listed under. You might be suggested to seek the advice of your physician or pharmacist if you’re not sure of any well being product you plan to make use of, or in the event you need assistance on your acute and persistent medical signs and circumstances

The potential unwanted side effects of the potent elements

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Acetaminophen

Acetaminophen is used for relieving ache, headache and fever. Merchandise which include acetaminophen or paracetamol, however shouldn’t have this declared on the label, pose a hazard to customers as unintended overdose can lead to liver harm.

Ciprofloxacin

Ciprofloxacin is an antibiotic used to deal with a variety of bacterial infections. It’s a prescription medication and needs to be used below medical supervision. Widespread unwanted side effects embody nausea, vomiting, diarrhoea and rash. Extreme unwanted side effects embody an elevated threat of tendon rupture, hallucinations and nerve harm.

Hydroquinone

Hydroquinone is a potent ingredient utilized in prescription medicines for the therapy of pores and skin circumstances. The ingredient is prohibited in skincare beauty merchandise and may solely be used below medical supervision, as hydroquinone could trigger dangerous results if not used correctly. The inappropriate use of hydroquinone may end in adjustments in pores and skin color and hypersensitivity reactions akin to rashes, redness, tingling and burning of pores and skin.

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Lead

Lead is a poisonous substance and poisoning can happen when it builds up within the physique, typically over months or years. It may well trigger long-term hurt together with kidney harm and elevated threat of hypertension.

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Levodopa (L-Dopa) – current in Mucuna pruriens seed extract

Levodopa is a prescription medication used within the therapy of Parkinson’s Illness and needs to be used below medical supervision. Levodopa could doubtlessly work together with medicines used to deal with hypertension. Negative effects of levodopa could embody low blood strain, irregular coronary heart fee and respiratory abnormalities.

Mercury

Mercury is a poisonous substance and is prohibited to be used as an ingredient in beauty merchandise. Common software of lotions containing mercury may result in rash, pores and skin discolouration and blotching. Persistent publicity to very excessive ranges of mercury in beauty merchandise may trigger poisonous results to the kidneys, digestive and nervous system, as it may be absorbed by way of the pores and skin. This might result in organ harm.

Phosphodiesterase Sort 5 (PDE-5) inhibitors

This class of medication consists of sildenafil and tadalafil. These medicines may cause critical unwanted side effects akin to strokes, coronary heart assaults, decreased or lack of imaginative and prescient and listening to and priapism (painful and exceedingly lengthy erections). If priapism is just not handled instantly, it might result in everlasting impotence. PDE-5 inhibitors are additionally not appropriate for sufferers with medical circumstances akin to sure heart-related issues or who’re on coronary heart drugs akin to nitrates. Deaths of sufferers discovered to be utilizing Sildenafil (PDE-5 inhibitor) whereas on nitrates have been reported abroad.

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Selective Androgen Receptor Modulators (SARMs)

Selective Androgen Receptor Modulators (SARMs)are chemical substances that mimic the results of the male hormone, testosterone. A few of these chemical substances are nonetheless present process analysis and no SARMs have been authorized for medical use in people. Utilizing such chemical substances may be harmful as not all their unwanted side effects are identified. The potential unwanted side effects could also be much like testosterone, akin to insomnia, irritability, aggressive behaviour, hypertension, and impotence. Examples embody cardarine (GW-501516), ligandrol (LGD-4033), myostine (YK-11), ostarine (MK 2866), testolone, MK 677 and RAD-140.

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Sibutramine

Sibutramine, beforehand a prescription weight reduction medication used within the therapy of weight problems, has been disallowed on the market in Singapore since 2010 as a result of elevated threat of coronary heart assaults and strokes. Using sibutramine has been related to critical unwanted side effects, together with hypertension, irregular heartbeats, hallucinations and temper swings.

Tretinoin

Tretinoin is a potent ingredient utilized in prescription medicines for the therapy of pores and skin circumstances and needs to be used below medical supervision. The ingredient is prohibited in skincare beauty merchandise. Inappropriate use of tretinoin may result in unwanted side effects akin to redness and peeling of pores and skin.

Yohimbe

Yohimbine is a potent medicinal ingredient. Negative effects related to yohimbine embody insomnia, nervousness, palpitations (sensation of coronary heart pounding, racing or skipped beats), sweating and blurred imaginative and prescient. Overdosage may cause low blood strain, speedy heartbeats, seizures, paralysis and coma. Deaths from overdose have additionally been reported.

Obtain pdf doc: Overseas Alert_2020_March1442 KB

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Matching search results: https://www.hsa.gov.sg/announcements/safety-alert/hsa-updates-on-products-found-overseas-that-contain-potent-ingredients-(march-2020)

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