MSD Animal Health Launches First Systemic Treatment for Poultry Red Mites EXZOLT® Eliminates Infestations in European Poultry Houses

MADISON, NJ, September 5, 2017 – MSD Animal Well being (often called Merck Animal Well being inside the USA and Canada) at the moment introduced the launch of EXZOLT® (fluralaner), the primary systemic therapy for poultry pink mite infestations – a novel method that nearly eliminates poultry pink mites in manufacturing homes of any measurement or kind, together with free vary. Conveniently administered by way of ingesting water, EXZOLT additionally improves poultry welfare by decreasing stress related to different types of therapy, and minimizes the publicity of staff and birds to chemical sprays.“Poultry pink mites are among the many most threatening pests in Europe, contributing to elevated stress ranges, decreased weight acquire and diminished egg high quality and manufacturing in infested birds,” says Dr. Taylor Barbosa, DVM, PhD, ACPV, Head of Poultry, MSD Animal Well being. “You will need to successfully deal with poultry pink mites as infestations not solely have an effect on the birds’ welfare, but additionally end in important financial losses for poultry producers.”Poultry pink mites are a high 5 reason for financial loss in European layer and breeder operations and in lots of different nations, as infestations trigger important stress to poultry, lower reproductive potential in males, egg manufacturing in females and weight acquire in younger birds.i The whole annual price of poultry pink mite infestations within the European egg laying trade is estimated to be €360 million, with greater than 430 million hens in all manufacturing sorts – pullets, breeders and layer hens – affected by infestations.Poultry pink mites are nocturnal feeders that disguise through the day beneath manure, on roosts and in cracks and crevices within the hen home, the place they lay eggs, making them troublesome to remove. Beforehand obtainable therapy choices are labor-intensive and/or have achieved restricted success in eliminating or controlling infestations. Mite infestations have an effect on poultry staff as effectively, inflicting gamasoidosis, a pores and skin situation characterised by rash and itching.The security of EXZOLT has been established via complete scientific analysis research. These research demonstrated that EXZOLT nearly eliminates poultry pink mites in manufacturing homes, and is protected for the birds and for human dealing with. No important antagonistic occasions had been reported.“With a zero day withdrawal interval, eggs from chickens handled with EXZOLT are protected to devour, making EXZOLT ideally suited for sustaining the well being, efficiency and welfare of flocks whereas persevering with to fulfill market calls for and avoiding financial loss for producers,” provides Dr. Barbosa.

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EXZOLT®

EXZOLT®, a first-of-its-kind product primarily based on the fluralaner molecule for the therapy of poultry pink mite infestations, works on the parasites’ nervous system and kills mites which have taken a blood meal, whereas remaining protected for the host animal. Chickens are handled throughout an infestation. This ensures that each grownup mites and their eggs are killed.Medical information from three European dose-confirmation research and an intensive nine-site subject examine confirmed EXZOLT offered digital elimination of poultry pink mite populations in all handled layer, breeder and/or pullet homes.In these research, the advisable EXZOLT dosage routine (0.5 mg/kg physique weight twice at a seven-day interval) achieved 99 p.c mite-killing efficacy for not less than 15 days, which spans two mite life cycles. EXZOLT begins working in mites inside 4 hours after mites begin to feed on handled chickens leading to efficient elimination of the mites.

About MSD Animal Well being

For greater than a century, MSD, a number one world biopharmaceutical firm, has been inventing for all times, bringing ahead medicines and vaccines for lots of the world’s most difficult ailments. MSD Animal Well being, often called Merck Animal Well being in the USA and Canada, is the worldwide animal well being enterprise unit of MSD.By its dedication to the Science of More healthy Animals™, MSD Animal Well being gives veterinarians, farmers, pet homeowners and governments one of many widest vary of veterinary prescribed drugs, vaccines and well being administration options and providers. MSD Animal Well being is devoted to preserving and enhancing the well being, well-being and efficiency of animals. It invests extensively in dynamic and complete R&D sources and a contemporary, world provide chain. MSD Animal Well being is current in additional than 50 nations, whereas its merchandise can be found in some 150 markets. For extra data, go to www.msd-animal-health.com or join with us on LinkedIn.

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Ahead-Trying Assertion of Merck & Co., Inc., Kenilworth, N.J., USA

This information launch of Merck & Co., Inc., Kenilworth, N.J., USA (the “firm”) consists of “forward-looking statements” inside the that means of the protected harbor provisions of the U.S. Non-public Securities Litigation Reform Act of 1995. These statements are primarily based upon the present beliefs and expectations of the corporate’s administration and are topic to important dangers and uncertainties. If underlying assumptions show inaccurate or dangers or uncertainties materialize, precise outcomes might differ materially from these set forth within the forward-looking statements.

Dangers and uncertainties embrace however usually are not restricted to, common trade situations and competitors; common financial components, together with rate of interest and forex trade fee fluctuations; the impression of pharmaceutical trade regulation and well being care laws in the USA and internationally; world tendencies towards well being care price containment; technological advances, new merchandise and patents attained by rivals; challenges inherent in new product improvement, together with acquiring regulatory approval; the corporate’s potential to precisely predict future market situations; manufacturing difficulties or delays; monetary instability of worldwide economies and sovereign danger; dependence on the effectiveness of the corporate’s patents and different protections for revolutionary merchandise; and the publicity to litigation, together with patent litigation, and/or regulatory actions.

The corporate undertakes no obligation to publicly replace any forward-looking assertion, whether or not because of new data, future occasions or in any other case. Extra components that might trigger outcomes to vary materially from these described within the forward-looking statements might be discovered within the firm’s 2016 Annual Report on Kind 10-Okay and the corporate’s different filings with the Securities and Change Fee (SEC) obtainable on the SEC’s Web web site (www.sec.gov).i Mites of poultry. Merck Veterinary Guide. Retrieved from http://www.merckvetmanual.com/poultry/ectoparasites/mites-of-poultry.

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Source: https://www.merck-animal-health.com/blog/2017/09/05/msd-animal-health-launches-first-systemic-treatment-for-poultry-red-mites-exzolt-eliminates-infestations-in-european-poultry-houses/

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