Treating Poultry Mite with EXZOLT® (fluralaner) Significantly Reduces Mite-Related Stress and Improves Poultry Well-Being

MADISON, N.J., September 19, 2019 – MSD Animal Well being, a division of Merck & Co., Inc., Kenilworth, N.J., USA, right this moment introduced knowledge from the primary examine below subject situations on stress-parameters in poultry, introduced on the twenty first World Veterinary Poultry Affiliation Congress (WVPAC 2019), September 16-20, in Bangkok, Thailand. It exhibits that treating poultry crimson mite with EXZOLT® (fluralaner) improved poultry well-being and lowered crimson mite infestation-related stress.

EXZOLT® is the primary systemic remedy for poultry crimson mite infestations. Conveniently administered through ingesting water, it employs a novel method that nearly eliminates poultry crimson mites in manufacturing homes of any measurement or sort, together with free-range.

The examine was carried out on chosen farms in Spain, Germany and France to guage the impact of EXZOLT® on crimson mite infestation-related stress in laying hens in numerous housing programs. Physiological, behavioral and well being parameters of mite-related stress have been measured earlier than and after remedy with EXZOLT®.

The examine discovered EXZOLT® lowered physiological parameters of stress, together with ranges of corticosterone within the blood, in addition to behavioral parameters, together with head, physique and wing shaking, head-scratching, preening plumage, light and extreme feather pecking, aggression, and exercise through the day and night time. Hens confirmed a return to regular or enchancment of stress indicators and a lowered incidence of comb discoloration, an indicator of blood loss, inside just a few days after the primary software of EXZOLT®. Outcomes have been constant throughout totally different housing programs, breeds and ages.i

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“Mite infestations considerably affect the welfare of chickens by inducing persistent stress and trigger financial loss for poultry producers by diminishing egg high quality and manufacturing,” mentioned Rik Koopman, DVM, International Technical Director, MSD Animal Well being. “The physiological stress brought on by poultry mite infestations, indicated by elevated ranges of the stress hormone corticosterone, has beforehand been studied solely below lab situations. We’re happy to share knowledge from the primary examine of mite-related stress below subject situations that present the advantages of EXZOLT® for chickens and producers.”

Poultry crimson mites are a top-five explanation for financial loss in European layer and breeder operations and in lots of different international locations, as infestations trigger important stress to poultry, lower reproductive potential in males, egg manufacturing in females and weight acquire in younger birds. The whole annual price of poultry crimson mite infestations within the European egg laying business is estimated to be 360 million euros, with greater than 430 million hens in all manufacturing varieties – pullets, breeders and layer hens – affected by infestations.

About EXZOLT® (fluralaner)EXZOLT®, a first-of-its-kind product based mostly on the fluralaner molecule for the remedy of poultry crimson mite infestations and kills mites which have taken a blood meal, whereas remaining secure for the host animal. Chickens are handled throughout an infestation. This ensures that each grownup mites and their nymphs are killed. EXZOLT® begins working in mites inside 4 hours after mites begin to feed on handled chickens, leading to efficient elimination of the mites.

Medical knowledge from three European dose-confirmation research and an in depth nine-site subject examine confirmed EXZOLT® offered digital elimination of poultry crimson mite populations in all handled layer, breeder and/or pullet homes. In these research, the beneficial EXZOLT® dosage routine (0.5 mg/kg physique weight twice at a seven-day interval) achieved 99 % mite-killing efficacy for a minimum of 15 days, which spans two mite life cycles.

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Please see prescribing info for EXZOLT® at

About MSD Animal Well beingFor greater than a century, MSD, a number one international biopharmaceutical firm, has been inventing for all times, bringing ahead medicines and vaccines for lots of the world’s most difficult illnesses. MSD Animal Well being, a division of Merck & Co., Inc., Kenilworth, N.J., USA, is the worldwide animal well being enterprise unit of MSD. By its dedication to the Science of More healthy Animals®, MSD Animal Well being presents veterinarians, farmers, pet homeowners and governments one of many widest ranges of veterinary prescription drugs, vaccines and well being administration options and companies in addition to an in depth suite of digitally linked identification, traceability and monitoring merchandise. MSD Animal Well being is devoted to preserving and enhancing the well being, well-being and efficiency of animals and the individuals who look after them. It invests extensively in dynamic and complete R&D assets and a contemporary, international provide chain. MSD Animal Well being is current in additional than 50 international locations, whereas its merchandise can be found in some 150 markets. For extra info, go to or join with us on LinkedIn and Twitter.

iPresented on the MSD Animal Well being WVPA Congress symposium, “Creative Options for the Hatchery & Breakthrough New Remedy for Poultry Mites, Thursday, September 19, 2019 on the twenty first World Veterinary Poultry Affiliation Congress (WVPAC 2019), Bangkok, Thailand.

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